CD127 / IL7R (Marker of T-Reg Cells) Antibody [IL7R/2751]

These antibodies are validated on HuProt™ Human Protein Microarrays containing over 21,000 full-length human proteins, including the specific target of interest. LEARN MORE

Additional information

Catalog Number: 3575-MSM1
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

In Stock
Catalog Number Formulation Size Price
3575-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3575-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3575-MSM1-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
  • ELISA
  • WB

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Western Blot (WB) 2-4ug/ml Western Blot Protocol

Product Properties

Antibody Type
Host
Mouse
Applications
Species Reactivity
Clone
IL7R/2751
Isotype
IgG2c
Light Chain
Kappa
Cellular Localization
Cell membrane, Secreted
Gene Name
Positive Control
Daudi or Jurkat cells. Tonsil, HeLa, K562, lymph node or spleen.
Immunogen
Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

Related Antibodies

Other Information

Functions
Key References
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
SwissProt
Chromosome Location
5p13.2
Mol. Weight of Antigen
52-72kDa
Alternate Names
Interleukin-7 receptor subunit alpha, CDw127, CD127; IL-7 receptor subunit alpha; IL-7R-alpha; IL7R; IL7RA; IL7R alpha; ILRA; Interleukin 7 receptor alpha chain; Interleukin 7 receptor

Summary

The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).

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