Printable Datasheet

CCN family member 2 Antibody [CCN2/14714]

In Stock
Catalog Number Formulation Size Price
1490-MSM5-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
1490-MSM5-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
1490-MSM5-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Extracellular matrix, Extracellular space, Secreted
Gene Name
CCN2
Positive Control
Expressed in bone marrow and thymic cells
Immunogen
Recombinant fragment (around aa 217-347) of human CCN2 protein
Alternate Names
CCN family member 2, CTGF|HCS24|IBP-8|IGFBP8|KMD|NOV2|SEMDLSL

Database Links

Entrez Gene ID
1490
SwissProt
P29279

Additional Information

Clone
CCN2/14714
Chromosome Location
6q23.2
Mol. Weight of Antigen
38.09kDa
Purification
Protein G

Related Antibodies

View All CCN2 Antibodies

Functions

  • Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Is involved in the stimulation of osteoblast differentiation and has a critical role in osteogenesis (PubMed:39414788). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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