Trial Size Available
Carrier-Free Available
Formalin-fixed, paraffin-embedded human ovarian carcinoma stained with Angiopoietin-1 Mouse Monoclonal Antibody (ANGPT1/3651). Inset: PBS instead of primary antibody; secondary only negative control.
Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with Angiopoietin-1 Mouse Monoclonal Antibody (ANGPT1/3651). Inset: PBS instead of primary antibody; secondary only negative control.
SDS-PAGE Analysis of Purified Angiopoietin-1 Mouse Monoclonal Antibody (ANGPT1/3651). Confirmation of Purity and Integrity of Antibody.
Western Blot Analysis of Human Liver, COLO38 and PC3 lysates using PPP2CA Mouse Monoclonal Antibody (ANGPT1/3651).
| Document Name | |
|---|---|
| Datasheet | Download Here |
| Material Safety Data Sheet | Download Here |
| Applications | Tested Dilutions | Protocol | Note |
|---|---|---|---|
| Immunohistochemistry (IHC) | 1-2ug/ml | IHC Protocol | 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes |
| Western Blot (WB) | 2-4ug/ml | Western Blot Protocol |
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This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.
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