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ADAMTS2 Antibody [ADAMTS2/14006]

In Stock
Catalog Number Formulation Size Price
9509-MSM3-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
9509-MSM3-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
9509-MSM3-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Summary

Cleaves the propeptides of type I and II collagen prior to fibril assembly (By similarity). Does not act on type III collagen (By similarity). Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form with reduced collagen-binding activity (PubMed:31152061).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Immunohistochemistry
Species Reactivity
Human
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Extracellular matrix, Extracellular space, Secreted
Gene Name
ADAMTS2
Positive Control
Expressed at high level in skin, bone, tendon and aorta and at low levels in thymus and brain
Immunogen
Recombinant fragment (around aa 1098-1205) of human ADAMTS2 protein
Alternate Names
A disintegrin and metalloproteinase with thrombospondin motifs 2, ADAM-TS2|ADAMTS-2|ADAMTS-3|EDSDERMS|NPI|PC I-NP|PCI-NP|PCINP|PCPNI|PNPI

Database Links

Entrez Gene ID
9509
SwissProt
O95450

Additional Information

Clone
ADAMTS2/14006
Chromosome Location
5q35.3
Mol. Weight of Antigen
134.75kDa
Purification
Protein G

Related Antibodies

View All ADAMTS2 Antibodies

Functions

  • Cleaves the propeptides of type I and II collagen prior to fibril assembly (By similarity). Does not act on type III collagen (By similarity). Cleaves lysyl oxidase LOX at a site downstream of its propeptide cleavage site to produce a short LOX form with reduced collagen-binding activity (PubMed:31152061).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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