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Recombinant IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody [IL3RA/17642RR]

Additional information

Catalog Number: 3563-RBM14
Gene:

Host:

Reactivity:

In Stock

Trial Size Available

Carrier-Free Available

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In Stock
Catalog Number Formulation Size Price
3563-RBM14-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3563-RBM14-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3563-RBM14-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
Recombinant IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody in SDS-PAGE

Recombinant IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified Recombinant IL3RA / CD123 (Acute Myeloid Leukemia Marker) Rabbit Monoclonal Antibody (IL3RA/17642RR). Confirmation of Purity and Integrity of Antibody.

  • IHC
  • Documents
  • Applications & Dilutions
  • Product Properties
  • other information

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunohistochemistry (IHC) 1-2ug/ml IHC Protocol 30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes

Product Properties

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry
Species Reactivity
Human
Clone
IL3RA/17642RR
Isotype
IgG
Light Chain
Kappa
Cellular Localization
Cell membrane
Gene Name
IL3RA
Immunogen
Recombinant fragment (around aa 26-171) of human IL3RA protein
Purification
Protein G
Storage & Stability
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

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Other Information

Functions
  • Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity).
PubMed Links
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
3563
SwissProt
P26951
Chromosome Location
X;Y
Mol. Weight of Antigen
43.33kDa
Alternate Names
Interleukin-3 receptor subunit alpha, CD123|IL-3R-alpha|IL3R|IL3RAY|IL3RX|IL3RY|hIL-3Ra

Summary

Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed:10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity).

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