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Recombinant Filaggrin (Keratinocyte Differentiation Marker) Antibody [FLG/9829R]

In Stock
Catalog Number Formulation Size Price
2312-RBM12-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
2312-RBM12-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
2312-RBM12-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol Note
Immunohistochemistry (IHC)
1-2ug/ml
IHC Protocol
30 min at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.

Product Properties & Targets

Antibody Type
Recombinant Rabbit Monoclonals
Host
Rabbit
Applications
Immunohistochemistry, Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cytoplasmic granule
Gene Name
FLG
Positive Control
Expressed in skin, thymus, stomach, tonsils, testis, placenta, kidney, pancreas, mammary gland, bladder, thyroid, salivary gland and trachea, but not detected in heart, brain, liver, lung, bone marrow, small intestine, spleen, prostate, colon, or adrenal gland (PubMed:19384417)
Immunogen
Recombinant fragment corresponding to the n-terminal region of the human Filaggrin protein
Alternate Names
Filaggrin, ATOD2|FLG-1|FLG1

Database Links

Entrez Gene ID
2312
SwissProt
P20930

Additional Information

Clone
FLG/9829R
Chromosome Location
1q21.3
Mol. Weight of Antigen
435.16kDa
Expression System
CHO Cells
Purification
Protein A

Related Antibodies

View All FLG Antibodies

Functions

  • Aggregates keratin intermediate filaments and promotes disulfide-bond formation among the intermediate filaments during terminal differentiation of mammalian epidermis.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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