Heregulin-1 / Neuregulin-1 (Breast and Urothelial Marker) Antibody [NRG1/2752]

These antibodies are validated on HuProt™ Human Protein Microarrays containing over 21,000 full-length human proteins, including the specific target of interest. LEARN MORE

Additional information

Catalog Number: 3084-MSM2
Reactivity:

Gene:

Host:

In Stock

Trial Size Available

Carrier-Free Available

In Stock
Catalog Number Formulation Size Price
3084-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
3084-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
3084-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
  • ELISA
  • IF

Documents

Document Name
Datasheet Download Here
Material Safety Data Sheet Download Here

Applications & Dilutions

Applications Tested Dilutions Protocol Note
Immunofluorescence (IF) 1-3ug/ml

Product Properties

Antibody Type
Host
Mouse
Applications
Species Reactivity
Clone
NRG1/2752
Isotype
IgG
Cellular Localization
Cell membrane, Membrane, Nucleus, Secreted
Gene Name
Positive Control
A431, Bladder or Thyroid Carcinoma., MCF-7 or T47D cells. Breast
Immunogen
Recombinant fragment of human Neuregulin-1 (NRG1) protein (around aa 21-242) (exact sequence is proprietary)
Storage & Stability
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Supplied as
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Limitations
This antibody is available for research use only and is not approved for use in diagnosis.

Related Antibodies

Other Information

Functions
Key References
Warranty
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Entrez Gene ID
SwissProt
Chromosome Location
8p12
Mol. Weight of Antigen
26-71kDa
Alternate Names
Pro-neuregulin-1, membrane-bound isoform, Acetylcholine receptor-inducing activity (ARIA); Breast cancer cell differentiation factor p45; Glial growth factor (GGF2); Heregulin-1; Heregulin, alpha (45kD, ERBB2 p185-activator); HGL; HRG1; HRGA; MST131; Neu Differentiation Factor (NDF); Neuregulin-1; NRG1; Sensory and Motor Neuron-Derived Factor (SMDF)

Summary

Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

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