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Transcription factor 7-like 1 Antibody [PCRP-TCF7L1-1A9]

In Stock
Catalog Number Formulation Size Price
83439-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
83439-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
83439-MSM2-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Nucleus
Gene Name
TCF7L1
Positive Control
Detected in hair follicles and skin keratinocytes, and at lower levels in stomach epithelium
Immunogen
Recombinant human TCF7L1 protein
Alternate Names
Transcription factor 7-like 1, TCF-3|TCF3

Database Links

Entrez Gene ID
83439
SwissProt
Q9HCS4

Additional Information

Clone
PCRP-TCF7L1-1A9
Chromosome Location
2p11.2
Mol. Weight of Antigen
62.63kDa
Purification
Protein G

Related Antibodies

View All TCF7L1 Antibodies

Functions

  • Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. Necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis (By similarity). Down-regulates NQO1, leading to increased mitomycin c resistance.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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