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TOX high mobility group box family member 3 Antibody [PCRP-TOX3-1A6]

In Stock
Catalog Number Formulation Size Price
27324-MSM6-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
27324-MSM6-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
27324-MSM6-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG1 / Kappa
Cellular Localization
Nucleus
Gene Name
TOX3
Positive Control
Expressed mainly in epithelial cells
Immunogen
Recombinant human TOX3 protein
Alternate Names
TOX high mobility group box family member 3, CAGF9|TNRC9

Database Links

Entrez Gene ID
27324
SwissProt
O15405

Additional Information

Clone
PCRP-TOX3-1A6
Chromosome Location
16q12.1
Mol. Weight of Antigen
63.34kDa
Purification
Protein G

Related Antibodies

View All TOX3 Antibodies

Functions

  • Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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