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Recombinant KLK7 (Kallikrein Related Peptidase 7) Antibody [rKLK7/13965]

In Stock
Catalog Number Formulation Size Price
5650-MSM8-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
5650-MSM8-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
5650-MSM8-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Western Blot (WB)
2-4ug/ml
Western Blot Protocol

Summary

May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at ’14-Tyr-|-Gln-15′ and insulin B chain at ‘6-Leu-|-Cys-7′, ’16-Tyr-|-Leu-17′, ’25-Phe-|-Tyr-26′ and ’26-Tyr-|-Thr-27’. Could play a role in the activation of precursors to inflammatory cytokines.

Product Properties & Targets

Antibody Type
Recombinant Mouse Monoclonals
Host
Mouse
Applications
Western Blot
Species Reactivity
Human
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Secreted
Gene Name
KLK7
Positive Control
Abundantly expressed in the skin and is expressed by keratinocytes in the epidermis
Immunogen
Recombinant fragment of human KLK7 protein (around aa 1-200)
Alternate Names
Kallikrein-7, PRSS6|SCCE|hK7

Database Links

Entrez Gene ID
5650
SwissProt
P49862

Additional Information

Clone
rKLK7/13965
Chromosome Location
19q13.41
Mol. Weight of Antigen
27.52kDa
Purification
Protein A

Related Antibodies

View All KLK7 Antibodies

Functions

  • May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-
  • -Gln-15' and insulin B chain at '6-Leu-
  • -Cys-7', '16-Tyr-
  • -Leu-17', '25-Phe-
  • -Tyr-26' and '26-Tyr-
  • -Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab produced in a mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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