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Follistatin / Activin Binding Protein Antibody [FST/4282]

In Stock
Catalog Number Formulation Size Price
10468-MSM2-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
10468-MSM2-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
10468-MSM2-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day

Applications & Dilutions

Applications Tested Dillution Protocol Note
Western Blot (WB)
2-4ug/ml

Summary

Follistatin is a single-chain glycosylated protein that inhibits follicle stimulating hormone (FSH) release. Alternative splicing of Follistatin mRNA yields two isoforms, FS315 and FS288. FS288 is the main cell-surface form and binds to surface heparin sulphate proteoglycans. FST/4282 recognizes recombinant human Follistatin 288, allowing for detection of FSH levels using various analysis methods. This antibody also works in a two site ELISA with FST/4281.

Product Properties & Targets

Antibody Type
Host
Mouse
Applications
Species Reactivity
Isotype / Light Chain
IgG1 /
Cellular Localization
Secreted
Gene Name
FST
Positive Control
Human testis or ovary.
Immunogen
Recognizes human Follistatin isoform FS288, raised against recombinant human FS288.
Alternate Names
Follistatin, Activin-binding protein, Follistatin, FS, FST, Active-binding protein

Database Links

Entrez Gene ID
SwissProt

Additional Information

Clone
FST/4282
Chromosome Location
5q11.2
Mol. Weight of Antigen
37kDa

Functions

  • Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).

Key References

  • Evans, L. (1998). Journal of Endocrinology 156.2; 275-82.

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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