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CREB3L3 Antibody [PCRP-CREB3L3-2D10]

In Stock
Catalog Number Formulation Size Price
84699-MSM1-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$259.00
84699-MSM1-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$559.00
84699-MSM1-P1ABX
Purified Ab WITHOUT BSA or Azide at 1.0mg/ml
100ug
$559.00
Flat Rate Domestic: $95 | Orders outside the US - Contact Us for Order Information | Ships next business day
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Applications & Dilutions

Applications Tested Dillution Protocol
Flow Cytometry (Flow)
1-2ug/million cells
Flow Cytometry Protocol
Immunofluorescence (IF)
1-3ug/ml

Summary

Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). May function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. Regulates FGF21 transcription (By similarity). Plays a crucial role in the regulation of triglyceride metabolism and is required for the maintenance of normal plasma triglyceride concentrations (PubMed:21666694).

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Applications
Flow Cytometry, Immunofluorescence
Species Reactivity
Human
Isotype / Light Chain
IgG2b / Kappa
Cellular Localization
Endoplasmic reticulum membrane, Nucleus
Gene Name
CREB3L3
Positive Control
Exclusively expressed in liver
Immunogen
Recombinant human CREB3L3 protein
Alternate Names
Cyclic AMP-responsive element-binding protein 3-like protein 3, CREB-H|CREBH|HYST1481|HYTG2

Database Links

Entrez Gene ID
84699
SwissProt
Q68CJ9

Additional Information

Clone
PCRP-CREB3L3-2D10
Chromosome Location
19p13.3
Mol. Weight of Antigen
49.08kDa
Purification
Protein G

Related Antibodies

View All CREB3L3 Antibodies

Functions

  • Transcription factor that may act during endoplasmic reticulum stress by activating unfolded protein response target genes. Activated in response to cAMP stimulation. In vitro, binds to the cAMP response element (CRE) and box-B element. Activates transcription through box-B element. Activates transcription through CRE (By similarity). May function synergistically with ATF6. In acute inflammatory response, may activate expression of acute phase response (APR) genes. May be involved in growth suppression. Regulates FGF21 transcription (By similarity). Plays a crucial role in the regulation of triglyceride metabolism and is required for the maintenance of normal plasma triglyceride concentrations (PubMed:21666694).

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
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