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CD109 Antibody [CD109/9949]

In Stock
Catalog Number Formulation Size Price
135228-MSM4-P0
Purified Ab with BSA and Azide at 200ug/ml
20ug
$229.00
135228-MSM4-P1
Purified Ab with BSA and Azide at 200ug/ml
100ug
$519.00
135228-MSM4-P1ABX
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
100ug
$519.00
Flat Rate Domestic: $60 | Orders outside the US - Contact Us for Order Information | Ships next business day
CD109 Antibody in SDS-PAGE

CD109 Antibody in SDS-PAGE

SDS-PAGE Analysis of Purified CD109 Mouse Monoclonal Antibody (CD109/9949). Confirmation of Purity and Integrity of Antibody.

CD109 Antibody in Immunohistochemistry (IHC (P))

CD109 Antibody in Immunohistochemistry (IHC (P))

Formalin-fixed, paraffin-embedded human parathyroid stained with CD109 Mouse Monoclonal Antibody (CD109/9949). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.

Summary

This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.

Product Properties & Targets

Antibody Type
Mouse Monoclonals
Host
Mouse
Species Reactivity
Human
Research Areas
Immunology
Isotype / Light Chain
IgG / Kappa
Cellular Localization
Cell membrane
Gene Name
CD109
Immunogen
Recombinant fragment (around aa300-500) of human CD109 protein (exact sequence is proprietary)
Alternate Names
CD109 antigen, B120, BRG1-associated factor 250, BRG1-associated factor 250a, Osa homolog 1, SWI-like protein, SWI/SNF complex protein p270, SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1, hELD, 150 KDa TGF beta 1 binding protein, 150 KDa TGF-beta-1-binding protein, 7D1 antibody 8A3, Activated T cell marker CD109, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, CD 109, CD109, CD109 antigen, CD109_HUMAN, CPAMD7, DKFZp762L1111, E123, FLJ38569, FLJ41966, Gov system alloantigens on platelets, p180, Platelet specific Gov antigen, Platelet-specific Gov antigen, r150, RP11 525G3.1, r150, CPAMD7

Database Links

Entrez Gene ID
135228
SwissProt
Q6YHK3

Additional Information

Clone
CD109/9949
Chromosome Location
6q13
Mol. Weight of Antigen
170kDa

Related Antibodies

View All CD109 Antibodies

Functions

  • Modulates negatively TGFB1 signaling in keratinocytes.

Key References

  • Flajollet, S., et al. 2007. Mol. Cell. Endocrinol. 270: 23-32.

PubMed Links

Storage & Stability

Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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