Helicobacter pylori (Catalase) [122 Amino Acid Residues]

Summary

The spiral shaped bacteriumHelicobacter pyloriis strongly associated with inflammation of the stomach and is also implicated in the development of gastric malignancy.H. pyloriis known to cause peptic ulcers and chronic gastritis in human. It is associated with duodenal ulcers and may be involved in development of adenocarcinoma and low-grade lymphoma of mucosa associated lymphoid tissue in the stomach.This antibody stains the individual H. pylori bacterium when it presents on the surface of the epithelium or in the cytoplasm of the epithelial cells in biopsy tissue sections from the antrum and body of the stomach.

Product Properties & Targets

Species Reactivity
Mol. Weight of Antigen
58kDa
Immunogen
Recombinant Helicobacter pylori Catalase protein fragment (around aa323-445) (exact sequence is proprietary)

Database Links

Entrez Gene ID
Unigene
SwissProt

Additional Information

Clone
122 Amino Acid Residues
Human Gene Symbol
Not Applicable
Chromosome Location
Not Applicable

Known Applications & Suggested Dilutions

  • Developing ELISA; Blocking Antibody Reaction in various Immunochemical Assays such as:; Flow Cytometry; Immunofluorescence; Western Blotting; Immunohistology etc.(Use 10-fold excess of the recombinant protein than the optimized concentration of antibody)Optimal use for a specific application should be determined.

Key References

  • Ito, T., Kobayashi, D., Uchida, K. et al. Helicobacter pylori invades the gastric mucosa and translocates to the gastric lymph nodes. Lab Invest 88, 664 681 (2008). https://doi.org/10.1038/labinvest.2008.33

Storage & Stability

Recombinant Protein with azide: store at -20 to -80 °C. Recombinant Protein is stable for 24 months. Non-hazardous. No MSDS required.

Limitations

This antibody is available for research use only and is not approved for use in diagnosis.

Supplied as

100ug/ml of purified recombinant protein. Prepared in 10mM PBS with 0.05% azide.

Warranty

There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.

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