Formalin-fixed, paraffin-embedded human bladder stained with TCF4 Mouse Monoclonal Antibody (TCF4/1705) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis Purified TCF4 Mouse Monoclonal Antibody (TCF4/1705). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of 1) HeLa and (2) HepG2 cell lysates using TCF4 Mouse Monoclonal Antibody (TCF4/1705).
Analysis of Protein Array containing more than 19,000 full-length human proteins using TCF4-Monospecific Mouse Monoclonal Antibody (TCF4/1705).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Recognizes a protein of 71kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.