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Home >> Antibodies >> Prostate Specific Acid Phosphatase (PSAP)

Prostate Specific Acid Phosphatase (PSAP)

Recombinant Rabbit Monoclonal Antibody [Clone ACPP/8409R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

SDS-PAGE Analysis Purified PSAP Recombinant Rabbit Monoclonal Antibody (ACPP/8409R). Confirmation of Purity and Integrity of Antibody.

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Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PSAP Recombinant Rabbit Monoclonal Antibody (ACPP/8409R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

Product Details

Synonyms

5'-nucleotidase (5'-NT); Acid phosphatase prostate; ACP3; Ecto-5'-nucleotidase; Prostatic acid phosphatase (PAP); Prostatic acid phosphatase; Thiamine monophosphatase (TMPase)

Positive Control

PC12 cells. Normal prostate or prostate carcinoma tissue.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa200-400) of human ACPP (exact sequence is proprietary)

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

45kDa

Specificity & Comments

Prostatic Acid Phosphatase (PSAP or PAP) is a member of the histidine acid phosphatase family. It is a non-specific phosphatase that is capable of dephosphorylating tyrosine residues as well as phospholipids under mildly acidic conditions. Prostatic specific acid phosphatase (PSAP) is involved in prostate epithelial differentiation. It is highly expressed in prostate, primary and metastatic carcinoma of the prostate. This marker may be helpful in pinpointing the site of origin in cases of metastatic carcinoma of the prostate, and is considered a more sensitive marker than PSA.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Genega EM, et al. Mod Pathol. 2000 Nov;13(11):1186-91.
  2. Street, S.E, et al. (2013) J Neurosci 33, 11314-22.

Bioinformatics

  •  Entrez Gene ID: 55
  •  Gene Symbol: ACPP
  •  SwissProt: P15309
  •  Chromosome Location: 3q22.1
  •  Unigene: 433060