Home >> Antibodies >> Progesterone Receptor (Marker of Progestin Dependence)

Progesterone Receptor (Marker of Progestin Dependence)

Mouse Monoclonal Antibody [Clone PR484]

Printable

Key References

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Key References

Bioinformatics

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Progesterone Receptor Mouse Monoclonal Antibody (PR484).

SDS-PAGE Analysis Purified Progesterone Receptor Mouse Monoclonal Antibody (PR484). Confirmation of Integrity and Purity of Antibody.

Formalin-fixed, paraffin-embedded human breast carcinoma stained with Progesterone Receptor Mouse Monoclonal Antibody (PR484).

SDS-PAGE Analysis Purified Progesterone Receptor Mouse Monoclonal Antibody (PR484). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor form A, Progesterone receptor form B

Positive Control

T47-D cells. Human breast cancers.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human Progesterone Receptor protein (PGR)

Cellular Localization

Nucleus

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

PR-A (81kDa) and PR-B (116kDa).

Specificity & Comments

This MAb is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.