2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)

PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)

Mouse Monoclonal Antibody [Clone PMEPA1/2696]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PMEPA1 Mouse Monoclonal Antibody (PMEPA1/2696).

img

Formalin-fixed, paraffin-embedded human colon carcinoma stained with PMEPA1 Mouse Monoclonal Antibody (PMEPA1/2696).

img

Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PMEPA1 Mouse Monoclonal Antibody (PMEPA1/2696).

img

SDS-PAGE Analysis Purified PMEPA1 Mouse Monoclonal Antibody (PMEPA1/2696). Confirmation of Purity and Integrity of Antibody.

img

Analysis of Protein Array containing more than 19,000 full-length human proteins using PMEPA1 Mouse Monoclonal Antibody (PMEPA1/2696).

Product Details

Synonyms

PMEPA; PMEPA1; Prostate transmembrane protein, androgen induced 1; Solid tumor-associated 1 protein; STAG1; TMEPAI; Transmembrane prostate androgen-induced protein; Transmembrane, prostate androgen induced RNA

Positive Control

Human prostate, breast or renal cell carcinoma tissue (IHC).

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human PMEPA1 protein

Cellular Localization

Cell surface. Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

32kDa

Specificity & Comments

PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Xu, L.L., et al. 2000. Genomics 66: 257-263.

Bioinformatics

  •  Entrez Gene ID: 56937
  •  Gene Symbol: PMEPA1
  •  SwissProt: Q96W9
  •  Chromosome Location: 20q13.31
  •  Unigene: 517155