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Home >> Antibodies >> NUT1 / NUTM1 / Snurportin 1

NUT1 / NUTM1 / Snurportin 1

Recombinant Rabbit Monoclonal Antibody [Clone SNUPN/7351R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human testis stained with NUTM1 Recombinant Rabbit Monoclonal Antibody (SNUPN/7351R). Inset: PBS instead of primary antibody; secondary only negative control.

Product Details

Synonyms

NUT; Nuclear Protein in Testis; C15orf55; FAM22H; NUT Family Member 1; DKFZp434O192; Chromosome 15 Open Reading Frame 55

Positive Control

Human testis.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa 900-1100) of human NUTM1 protein (exact sequence is proprietary)

Cellular Localization

Nucleus. Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

120kDa

Specificity & Comments

NUTM1 (NUT Midline Carcinoma Family Member 1) is a Protein Coding gene. Diseases associated with NUTM1 include Nut Midline Carcinoma and Spindle Cell Sarcoma. Among its related pathways are Chromatin Regulation / Acetylation. An important paralog of this gene is NUTM2G.Plays a role in the regulation of proliferation. Regulates TERT expression by modulating SP1 binding to TERT promoter binding sites.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Luo, W., et al. NUTM1-Rearranged Neoplasms€”A Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular Alterations€”An Updated Review. Curr. Oncol. 2021, 28, 4485-4503. https://doi.org/10.3390/curroncol28060381

Bioinformatics

  •  Entrez Gene ID: 10073
  •  Gene Symbol: NUTM1
  •  SwissProt: Q86Y26
  •  Chromosome Location: 15q24.2
  •  Unigene: 29919