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Napsin A (Lung Adenocarcinoma Marker)

Recombinant Rabbit Monoclonal Antibody [Clone NAPSA/7043R]

Printable

Bioinformatics

Catalog #

Size

20 ug

100 ug

Price (USD)

219.00

499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA at 1.0mg/ml

Performance Guarantee

Catalog No

Size

20 ug

100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml

Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

219.00

499.00

Printable

Bioinformatics

Formalin-fixed, paraffin-embedded human lung stained with Napsin A Recombinant Rabbit Monoclonal Antibody (NAPSA/7043R). Inset: PBS instead of primary antibody, secondary negative control.

SDS-PAGE Analysis Purified Napsin A Mouse Monoclonal Antibody (NAPSA/7043R). Confirmation of Integrity and Purity of Antibody.

Formalin-fixed, paraffin-embedded human lung stained with Napsin A Recombinant Rabbit Monoclonal Antibody (NAPSA/7043R). Inset: PBS instead of primary antibody, secondary negative control.

SDS-PAGE Analysis Purified Napsin A Mouse Monoclonal Antibody (NAPSA/7043R). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA

Positive Control

Human lung or lung adenocarcinoma.

Known Applications & Suggested Dilutions

IHC-P More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human Napsin-A protein fragment (aa1-100) (exact sequence is proprietary)

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG, kappa

Mol. Weight of Antigen

37kDa

Specificity & Comments

Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.