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Home >> Antibodies >> Mitochondria (Marker for Human Cells, Granular RCC's & Salivary Tumors)

Mitochondria (Marker for Human Cells, Granular RCC's & Salivary Tumors)

Recombinant Rabbit Monoclonal Antibody [Clone MTC02/2860R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Pancreas stained with Mitochondria Rabbit Recombinant Monoclonal Antibody (MTC02/2860R).

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SDS-PAGE Analysis Purified Mitochondria Rabbit Recombinant Monoclonal (MTC02/2860R). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Not Known

Positive Control

HeLa or HepG2 cells. Hepatic carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Immunogen

Semi-Purified mitochondrial preparation

Cellular Localization

Mitochondria in cytoplasm

Species Reactivity

Human. Does not react with Mouse or Rat.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

60kDa

Specificity & Comments

This MAb recognizes a 60kDa antigen associated with the mitochondria in human cells. It can be used to stain mitochondria in cell or tissue preparations and can be used as a mitochondrial marker in subcellular fractions. It produces a spaghetti-like pattern in normal and malignant cells. This antibody is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells, including neurons and embryonic stem cells. Immunostaining pattern with anti-mitochondrial MAb has been reported as a useful discriminatory adjunct in the complex differential diagnosis of granular renal cell tumors. Reportedly, this MAb facilitates the classification of salivary tumors.

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200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Key References

  1. Tickoo SK, et al. Am J Surg Pathol. 1997;21(8):922-30.
  2. Vera-Sempere F, et al. Acta Otorrinolaringol Esp. 2011;62(1):1-9.

Bioinformatics

NBT02860