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Home >> Antibodies >> Mesothelin (Mesothelial Marker)

Mesothelin (Mesothelial Marker)

Biotinylated Mouse Monoclonal Antibody [Clone MSLN/2131]

Catalog #


0.5 ml at 100ug/ml

Price (USD)



Purified Ab conjugated to Biotin

Catalog No


0.5 ml at 100ug/ml


Purified Ab conjugated to Biotin

Price (USD)


Formalin-fixed, paraffin-embedded human lung stained with Biotin-conjugated Mesothelin Mouse Monoclonal Antibody (MSLN/2131).


Formalin-fixed, paraffin-embedded human endometrial carcinoma stained with Biotin-conjugated Mesothelin Mouse Monoclonal Antibody (MSLN/2131).


SDS-PAGE Analysis
Purified Mesothelin Mouse Monoclonal Antibody (MSLN/2131) (unconjugated).
Confirmation of Integrity and Purity of the Antibody.


Analysis of Protein Array containing more than 19,000 full-length human proteins using Mesothelin-Monospecific Mouse Monoclonal Antibody (MSLN/2131).

Product Details


CAK1; Megakaryocyte potentiating factor; Mesothelin; MSLN; SMR; SMRP

Positive Control

CAPAN-2 or HeLa cells. Lung Mesothelioma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.


Recombinant fragment (around aa 273-407) of human Mesothelin (MSLN) protein (exact sequence is proprietary)

Cellular Localization

Cell Surface and Secreted

Species Reactivity

Human, Mouse and Rat.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

40kDa (Mature form); 69kDa (Precursor)

Specificity & Comments

Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.

Related Products

Antibody purified from Bioreactor Concentrate by Protein A/G and conjugated to Biotin. Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.

Key References

  1. Chang, K. and Pastan, I. 1996. Molecular cloning of Mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc. Natl. Acad. Sci. USA 93: 136-140.


  •  Entrez Gene ID: 10232
  •  Gene Symbol: MSLN
  •  SwissProt: Q13421
  •  Chromosome Location: 16p13.3
  •  Unigene: 408488