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Home >> Antibodies >> Melanoma Antigen Family A, 4 / MAGEA4

Melanoma Antigen Family A, 4 / MAGEA4

Mouse Monoclonal Antibody [Clone CPTC-MAGEA4-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
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Formalin-fixed, paraffin-embedded human Testis stained with MAGEA4 Mouse Monoclonal Antibody (CPTC-MAGEA4-1).

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SDS-PAGE Analysis Purified MAGEA4 Mouse Monoclonal Antibody (CPTC-MAGEA4-1). Confirmation of Purity and Integrity of Antibody

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Analysis of Protein Array containing more than 19,000 full-length human proteins using MAGEA4 Mouse Monoclonal Antibody (CPTC-MAGEA4-1).

Product Details

Synonyms

CT1.4; MAGE-41; MAGE-X2; MAGE4; MAGE4A; MAGE4B; cancer/testis antigen 1.4; Melanoma-associated antigen 4

Positive Control

HepG2 cell lysate; melanoma, testes and placenta.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human MAGEA4 protein

Cellular Localization

Cytoplasmic and nuclear.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2c, kappa

Mol. Weight of Antigen

45-50kDa

Specificity & Comments

The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors, and based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta.

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200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Rogner, UC, et al. Genomics., U.S. National Library of Medicine, 10 Oct. 1995.

Bioinformatics

  •  Entrez Gene ID: 4103
  •  Gene Symbol: MAGEA4
  •  SwissProt: P43358
  •  Chromosome Location: Xq28
  •  Unigene: 37107
NBT02246