Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with Monospecific Mouse Monoclonal Antibody (SPM518) to Mammaglobin.
SDS-PAGE Analysis of Purified Monospecific Mouse Monoclonal Antibody (SPM518) to Mammaglobin. Confirmation of purity and integrity.
Western Blot Analysis of Human MCF-7,T47D and MDA-231 cell lysate using Monospecific Mouse Monoclonal Antibody (SPM518) to Mammaglobin.
Analysis of Protein Array containing >19,000 full-length human proteins using Mammaglobin (SCGB2A2) Mouse Monoclonal Antibody (SPM518)
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues.Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.