Formalin-fixed, paraffin-embedded human tonsil stained with LEF1 Mouse Monoclonal Antibody (LEF1/6764). HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human tonsil stained with LEF1 Mouse Monoclonal Antibody (LEF1/6764). Inset: PBS instead of primary antibody; secondary only negative control.
Analysis of Protein Array containing more than 19,000 full-length human proteins using LEF1-Monospecific Mouse Monoclonal Antibody (LEF1/6764).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Lymphoid Enhancing Factor 1 (LEF1) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.