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Home >> Antibodies >> KLF12

KLF12

MouseMonoclonal Antibody [Clone PCRP-KLF12-1E3]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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SDS-PAGE Analysis Purified KLF12 Mouse Monoclonal Antibody (PCRP-KLF12-1E3). Confirmation of Purity and Integrity of Antibody.

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Immunofluorescence analysis of PFA-fixed HeLa cells. KLF12 Mouse Monoclonal Antibody (PCRP-KLF12-1E3) followed by goat anti-mouse IgG-CF488 (green).

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Flow cytometric analysis of PFA-fixed HeLa cells. KLF12 Mouse Monoclonal Antibody (PCRP-KLF12-1E3) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using KLF12 Mouse Monoclonal Antibody (PCRP-KLF12-1E3).

Product Details

Synonyms

AP-2rep, AP2REP, HSPC122

Positive Control

HeLa or 293T cells.Human lymph node, spleen or colon.

Known Applications & Suggested Dilutions

IP, Flow Cyt, IF         More Details

Immunoprecipitation (1-2ug per 100-500ug of total protein)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human KLF12 protein

Cellular Localization

Nucleus.

Species Reactivity

Human. Predicted to react with Mouse and Rat.

Host / Ig Isotype

Mouse/ IgG1

Mol. Weight of Antigen

44.24kDa

Specificity & Comments

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Sutcliffe EG, et al. Cancer Genet, 2020 Aug. PMID 32805687

Bioinformatics

  •  Entrez Gene ID: 11278
  •  Gene Symbol: KLF12
  •  SwissProt: Q9Y4X4
  •  Chromosome Location: 13q22.1
  •  Unigene: 729350, 373857