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Home >> Antibodies >> KIF2C (Kinesin Family Member 2C) / MCAK

KIF2C (Kinesin Family Member 2C) / MCAK

Mouse Monoclonal Antibody [Clone KIF2C/4704]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Formalin-fixed, paraffin-embedded human testis stained with KIF2C Mouse Monoclonal Antibody (KIF2C/4704) at 2ug/ml. Inset: PBS instead of primary antibody; secondary only negative control.

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Formalin-fixed, paraffin-embedded human testis stained with KIF2C Mouse Monoclonal Antibody (KIF2C/4704) at 2ug/ml. HIER: Tris/EDTA, pH9.0, 45min. 2°: HRP-polymer, 30min. DAB, 5min.

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Western blot analysis of huma testis tissue lysate using KIF2C Mouse Monoclonal Antibody (KIF2C/4704) at 2ug/ml.

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SDS-PAGE Analysis Purified KIF2C Mouse Monoclonal Antibody (KIF2C/4704). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using KIF2C / MCAK Mouse Monoclonal Antibody (KIF2C/4704).

Product Details

Synonyms

4930402F02Rik; CT139; ESTM5; Kinesein Family Member 2C; kinesin like 6 (mitotic centromere associated kinesin); Kinesin like protein 6; Kinesin like protein KIF2C; KNSL6; MCAK; MGC11883; Mitotic centromere associated kinesin; OTTHUMP00000010066; X83316

Positive Control

Human thymus or testis. Isoform 2 is testis-specific.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa500-700) of human KIF2C protein (exact sequence is proprietary)

Cellular Localization

Cytoplasm. Nucleus.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

75/81kDa

Specificity & Comments

Kinesin family member 2c (KIF2C), alternately known as mitotic centromere associated kinesin (MCAK), is a member of the kinesin-like family of proteins. KIF2C is a cytoplasmic and nuclear protein, present throughout the cell cycle. KIF2C associates with the centromere early in prophase, and disassociates after telophase. KIF2C is abundant in thymus and testis, and present at lower levels in small intestine, the mucosal lining of the colon, and placenta. Human KIF2C maps to chromosome 1p34.1.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Marder RJ et. al. Lab Invest 52: 497-504, 1985.

Bioinformatics

  •  Entrez Gene ID: 11004
  •  Gene Symbol: KIF2C
  •  SwissProt: Q99661
  •  Chromosome Location: 1p34.1
  •  Unigene: 720061