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Home >> Antibodies >> IL-6 (Interleukin-6), Mouse

IL-6 (Interleukin-6), Mouse

Rat Monoclonal Antibody [Clone MP5-20F3]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

B cell differentiation factor; B-cell stimulatory factor 2 (BSF-2); CTL differentiation factor (CDF); Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HPGF; HSF; Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; Interferon beta-2 (IFNB2)

Positive Control

Mouse heart.

Known Applications & Suggested Dilutions

Neut. Studies, Flow Cyt, IF         More Details

Neutralization Studies (Order Ab without Azide)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant Mouse IL-6 protein

Cellular Localization

Cytoplasmic and extracellular (secreted)

Species Reactivity

Mouse. Does not react with Human or Rat.

Host / Ig Isotype

Rat / IgG1, kappa

Mol. Weight of Antigen

21kDa

Specificity & Comments

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. O'Connell PJ, et al. 2006. Blood 107:1010. (ELISA Capture)
  2. Rochman I, et al. 2005. J. Immunol. 174:4761. (Neut)
  3. Abrams J, et al. 1992. Immunol. Rev. 127:5. (ELISA Capture, Neut)
  4. Abrams J, 1995. Curr. Prot. Immunol. John Wiley and Sons, New York. Unit 6.20. (ELISA Capture)
  5. Sander B, et al. 1993. J. Immunol. Meth. 166:201. (ELISA Capture, Neut)
  6. Litton M, et al. 1994. J. Immunol Meth. 175:47. (IHC)
  7. Finkelman F, et al. 2003. Curr. Prot. Immunol. John Wiley Sons, New York. Unit 6.28. (In Vivo Capture)
  8. Starnes HF Jr, et al. 1990. J. Immunol. 145:4185. (Neut)
  9. Riedemann NC, et al. 2003. J. Immunol. 170:503. (Neut)

Bioinformatics

  •  Entrez Gene ID: 16193
  •  SwissProt: P08505
  •  Chromosome Location: 5 B1 (Mouse)
  •  Unigene: 1019
NBT00663