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Home >> Antibodies >> IL-4 (Interleukin-4), Mouse

IL-4 (Interleukin-4), Mouse

Rat Monoclonal Antibody [Clone 11B11]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified IL-4 Rat Monoclonal Antibody (11B11). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

B cell growth factor 1 (BCGF1); B cell IgG differentiation factor; B-Cell Stimulatory Factor 1 (BSF1); Binetrakin; IGG1 induction factor; IL4; Il4e12; Interleukin 4 variant 2; Interleukin 4, isoform 1; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra

Positive Control

Spleen, Thymus or Lymph Node.

Known Applications & Suggested Dilutions

ELISA, Neut. Studies, Flow Cyt, IF         More Details

ELISA (For coating, order Ab without BSA & Azide)
Neutralization Studies (Order Ab without BSA & Azide)
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Partially Purified native Mouse IL-4

Cellular Localization

Cytoplasmic and extracellular (secreted)

Species Reactivity

Mouse. Does not react with Human.

Host / Ig Isotype

Rat / IgG1, kappa

Mol. Weight of Antigen

13-14kDa

Specificity & Comments

IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor, which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development. IL-4 is expressed primarily by activated Th2 cells and NK cells, and at lower levels by mast cells, and basophils. IL-4 signals through the IL-4R, and dendritic cell IL-12.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Dzhagalov I, et al. 2007. J. Immunol. 178:2113. (ELISA)
  2. Xu G, et al. 2007. J. Immunol. 179:5358. (ELISA)
  3. Hara M, et al. 2001. J. Immunol. 166:3789. (Neutralization)
  4. Charles N, et al. 2010. Nat. Med. 16:701. (FC)
  5. Wang W, et al. 2007. J. Immunol. 178:4885. (Neutralization)
  6. Openshaw P, et al. 1995. J. Exp. Med. 182:1357. (ICC)
  7. Litton M, et al. 1994. J. Immunol. Methods 175:47. (IHC)
  8. Zavorotinskaya T, et al. 2003. Mol. Ther. 7:155. (IP)
  9. Fan WY, et al. 2001. Exp. Biol. Med. 226:1045. (IHC)

Bioinformatics

  •  Entrez Gene ID: 16189
  •  SwissProt: P07750
  •  Chromosome Location: 11 B1.3; 11 31.97 cM (Mouse)
  •  Unigene: 276360
NBT02008