Formalin-fixed, paraffin-embedded human Tonsil stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).
Formalin-fixed, paraffin-embedded human Lymph Node stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).
Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531).
SDS-PAGE Analysis Purified IL3RA/CD123 Mouse Monoclonal Antibody (IL3RA/1531). Confirmation of Integrity and Purity of Antibody.
Analysis of Protein Array containing >19,000 full-length human proteins using CD123 Mouse Monoclonal Antibody (IL3RA/1531)
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y.