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Home >> Antibodies >> IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)

IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210)

Rat Monoclonal Antibody [Clone 1B1.3a]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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SDS-PAGE Analysis Purified IL-10R1 Rat Monoclonal Antibody (1B1.3a). Confirmation of Integrity and Purity of Antibody.

Product Details

Synonyms

CD210 antigen; CDw210a; IBD28; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA IL10RIL-10R subunit alpha; interleukin 10 receptor, alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1

Positive Control

MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.

Known Applications & Suggested Dilutions

Neut. Studies, Flow Cyt, IF         More Details

Neutralization Studies (Order Ab without Azide)
Flow Cytometry (0.5-1ug/million cells in 0.1ml)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Purified recombinant extracellular region of Mouse IL10RA

Cellular Localization

Cell Surface

Species Reactivity

Mouse. Does not react with Human.

Host / Ig Isotype

Rat / IgG1, kappa

Mol. Weight of Antigen

90-110kDa

Specificity & Comments

This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Wang W, et al. 2004. FASEB J. 18:1043. (Neutralization
  2. Vieira PL, et al. 2004. J. Immunol. 172:5986. (Neutralization)

Bioinformatics

  •  Entrez Gene ID: 16154
  •  SwissProt: Q61727
  •  Chromosome Location: 9 A5.2; 9 24.84 cM (Mouse)
  •  Unigene: 379327
NBT02001