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Home >> Antibodies >> HPV-16 (Human Papilloma Virus 16)

HPV-16 (Human Papilloma Virus 16)

Mouse Monoclonal Antibody [Clone HPV16L1/1058]

Catalog #

Size

0.5 ml at 100ug/ml

Price (USD)

429.00

Formulation

Purified Ab conjugated to CF488

Catalog No

Size

0.5 ml at 100ug/ml

Formulation

Purified Ab conjugated to CF488

Price (USD)

429.00

Product Details

Synonyms

HPV-16; HPV-16 capsid; HPV16 L1; HPV16 major capsid protein L1; Human papillomavirus type 16 L1; Human papillomavirus type 16 major capsid protein L1

Positive Control

HPV-16 infected cells. Cervical tissue.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Flow Cytometry (5ul per test per one million cells or 5ul per 100ul of whole blood)
Immunofluorescence (1:50-1:100)
Optimal dilution for a specific application should be determined.

Immunogen

Human papilloma virus type 16, major capsid protein L1

Cellular Localization

Nuclear

Species Reactivity

Type 16 of Human Papilloma Virus (HPV-16).

Host / Ig Isotype

Mouse / IgG2a, kappa

Mol. Weight of Antigen

57kDa

Specificity & Comments

Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.

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Key References

  1. McLean CS, J Clin Pathol, 1990; 43:488-492.

Bioinformatics

NBT01058