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Home >> Antibodies >> Heart Fatty Acid Binding Protein (H-FABP) / FABP3

Heart Fatty Acid Binding Protein (H-FABP) / FABP3

Recombinant Mouse Monoclonal Antibody [Clone rFABP3/8534]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
img

Formalin-fixed, paraffin-embedded human heart stained with FABP3 Recombinant Mouse Monoclonal Antibody (rFABP3/8534). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.

img

SDS-PAGE Analysis Purified FABP3 Recombinant Mouse Monoclonal Antibody (rFABP3/8534). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

422 protein; Cardiac Fatty Acid Binding Protein; Fatty acid binding protein 11 (FABP11); Fatty acid binding protein 3, muscle and heart (mammary derived growth inhibitor); H-FABP; Heart type fatty acid binding protein; M FABP; Mammary derived growth inhibitor; MDGI; Muscle fatty acid binding protein; Mylein protein P2 homolog / adopocyte

Positive Control

Human heart or skeletal muscle.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)
(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Human recombinant FABP3 protein fragment (around aa1-127) (exact sequence is proprietary)

Cellular Localization

Cytoplasm.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

15kDa

Specificity & Comments

The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants.

Related Products



200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Watanabe, K., et al. (1993). Immunohistochemical distribution of heart-type fatty acid-binding protein immunoreactivity in normal human tissues and in acute myocardial infarct. The Journal of pathology, 170(1), 59-65. https://doi.org/10.1002/path.1711700110

Bioinformatics

  •  Entrez Gene ID: 2170
  •  Gene Symbol: FABP3
  •  SwissProt: P05413
  •  Chromosome Location: 2p11.2
  •  Unigene: 657242