Formalin-fixed, paraffin-embedded human pituitary stained with Growth Hormone Recombinant Rabbit Monoclonal Antibody (GH/8215R). HIER: Tris/EDTA, pH9.0, 45min. 2: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human placenta stained with Growth Hormone Recombinant Rabbit Monoclonal Antibody (GH/8215R). Inset: PBS instead of primary antibody; secondary only negative control.
SDS-PAGE Analysis Purified Growth Hormone Recombinant Rabbit Monoclonal Antibody (GH/8215R). Confirmation of Purity and Integrity of Antibody.
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).