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Home >> Antibodies >> Glycophorin A / CD235 (Red Blood Cell Marker)

Glycophorin A / CD235 (Red Blood Cell Marker)

Mouse Monoclonal Antibody [Clone SPM183]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

Blood group--MN locus; GPA; GPErik; GpMiIII; GPSAT; GYPA; MN sialoglycoprotein; MNS; PAS2; Sialoglycoprotein alpha

Positive Control

Erythrocytes.

Known Applications & Suggested Dilutions

Flow Cyt, IF         More Details

Erythrocyte Agglutination
Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Human erythrocytes treated with neuraminidase

Cellular Localization

Cell surface

Species Reactivity

Human. Cow.

Host / Ig Isotype

Mouse / IgM, kappa

Mol. Weight of Antigen

39kDa

Specificity & Comments

Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A. It reacts with a peptide epitope on the extracellular domain of human glycophorin. Glycophorin A is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorins acts as the receptor for Sandei virus and parvovirus.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Cartron JP and Rahuel C. Human erythrocyte glycophorins: protein and gene structure analyses. Transfus Med Rev 1992,6(2):63-92
  2. Gahmberg CG et al. Biosynthesis of the major human red cell sialoglycoprotein, glycophorin A. A review. Rev Fr Transfus Immunohematol 1981,24(1):53-73
  3. Rahuel C et al. Post-transcriptional regulation of the cell surface expression of glycophorins A, B, and E. J Biol Chem 1994, 269(52):32752-8
  4. Wybenga LE et al. Glycophorin as a receptor for Sendai virus. Biochemistry 1996,35(29):9513-8
  5. Thacker TC and Johnson FB. Binding of bovine parvovirus to erythrocyte membrane sialylglycoproteins. J Gen Virol 1998, 79:2163-9

Bioinformatics

NBT00865