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Home >> Antibodies >> GLUT-1 (Tumor Progression and Mesothelioma Marker)

GLUT-1 (Tumor Progression and Mesothelioma Marker)

Recombinant Rabbit Monoclonal Antibody [Clone GLUT1/3132R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Tongue stained with GLUT-1 Recombinant Rabbit Monoclonal Antibody (GLUT1/3132R).

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SDS-PAGE Analysis Purified GLUT-1 Recombinant Rabbit Monoclonal Antibody (GLUT1/3132R). Confirmation of Purity and Integrity of Antibody.

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Flow Cytometric Analysis of K562 cells using GLUT-1 Recombinant Rabbit Monoclonal Antibody (GLUT1/3132R) followed by goat anti-rabbit IgG-CF488 (Blue); Isotype Control (Red).

Product Details

Synonyms

Erythrocyte/hepatoma glucose transporter; Glucose transporter type-1; GLUT1; GLUT1DS; GLUTB; GT1; GTG1; Gtg3; HepG2 glucose transporter; PED; RATGTG1; Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)

Positive Control

K562, A431, MDA-MB-231 cells. Erythrocytes. Mesothelioma or breast, colon and ovarian carcinoma.

Known Applications & Suggested Dilutions

ELISA, Flow Cyt, IHC-P         More Details

ELISA (For coating use Ab at 1-2ug/ml order Ab without BSA)
Flow Cytometry (1-2ug/million cells)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment of human GLUT1 protein (around aa 203-305) (exact sequence is proprietary)

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

55kDa

Specificity & Comments

Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative).

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200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bioinformatics

  •  Entrez Gene ID: 6513
  •  Gene Symbol: SLC2A1
  •  SwissProt: P11166
  •  Chromosome Location: 1p34.2
  •  Unigene: 473721
NBT03132