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Home >> Antibodies >> FOXB2 (Transcription Factor)

FOXB2 (Transcription Factor)

Mouse Monoclonal Antibody [Clone PCRP-FOXB2-2B2]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

219.00
499.00
499.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

219.00
499.00
499.00
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Flow cytometric analysis of PFA-fixed HeLa cells. FOXB2 Mouse Monoclonal Antibody (PCRP-FOXB2-2B2) followed by goat anti-mouse IgG-CF488 (blue); isotype control (red).

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SDS-PAGE Analysis Purified FOXB2 Mouse Monoclonal Antibody (PCRP-FOXB2-2B2). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using FOXB2-Monospecific Mouse Monoclonal Antibody (PCRP-FOXB2-2B2).

Product Details

Synonyms

bA159H20.4; Forkhead box B2; Forkhead box protein B2; FOXB 2; Foxb2

Positive Control

HeLa or HepG2 cells.

Known Applications & Suggested Dilutions

ELISA, IP, Flow Cyt         More Details

ELISA (For coating, order antibody without BSA)
Immunoprecipitation (1-2ug per 100-500ug of total protein (1ml of cell lysate))
Flow Cytometry (1-2ug/million cells)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment (around aa1-200) of human FOXB2 protein (exact sequence is proprietary)

Cellular Localization

Nucleus.

Species Reactivity

Human. Predicted to react in Mouse and Rat.

Host / Ig Isotype

Mouse / IgG2a

Mol. Weight of Antigen

45.58kDa

Specificity & Comments

The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

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200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Blackshaw S, et al. Nature methods 15.5 (2018 May): 330-338.

Bioinformatics

  •  Entrez Gene ID: 442425
  •  Gene Symbol: FOXB2
  •  SwissProt: Q5VYV0
  •  Chromosome Location: 9q21.2
  •  Unigene: 553843