Flow cytometric analysis of PFA-fixed HeLa cells. FOXB2 Mouse Monoclonal Antibody (PCRP-FOXB2-2B2) followed by goat anti-mouse IgG-CF488 (blue); isotype control (red).
SDS-PAGE Analysis Purified FOXB2 Mouse Monoclonal Antibody (PCRP-FOXB2-2B2). Confirmation of Purity and Integrity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using FOXB2-Monospecific Mouse Monoclonal Antibody (PCRP-FOXB2-2B2).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.