Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with FOLH1 (PSMA) Mouse Monoclonal Antibody (SPM500).
SDS-PAGE Analysis Purified FOLH1 (PSMA) Mouse Monoclonal Antibody (SPM500). Confirmation of Integrity and Purity of Antibody.
Western Blot Analysis of human LNCaP cell lysate using FOLH1 (PSMA) Mouse Monoclonal Antibody (SPM500).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Folate hydrolase 1 (FOLH1), also known as Prostate-specific membrane antigen (PSMA), is a type II transmembrane glycoprotein belonging to the M28 peptidase family. FOLH1 has two enzymatic activities, one as a prostate-specific integral membrane folate hydrolase and the other as a carboxypeptidase In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.