Formalin-fixed, paraffin-embedded human Cerebellum stained with FCGRT Mouse Monoclonal Antibody (FCGRT/2932).
Formalin-fixed, paraffin-embedded human Testicular Cancer stained with FCGRT Mouse Monoclonal Antibody (FCGRT/2932).
SDS-PAGE Analysis Purified FCGRT Mouse Monoclonal Antibody (FCGRT/2932). Confirmation of Integrity and Purity of Antibody.
Analysis of Protein Array containing >19,000 full-length human proteins using FCGRT Mouse Monoclonal Antibody (FCGRT/2932)
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. FCGRT is present in the intestinal epithelium of neonates and mediates the selective uptake of immunoglobulin G (IgG) in mothers' milk, thereby helping newborn to acquire passive immunity. FCGRT is comprised of a heavy chain and -2-Microglobulin. FCGRT localizes in endosomes of vascular endothelial cells and selectively recycles IgG to the cell surface, thus protecting IgG from lysosomal degradation.