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Home >> Antibodies >> Ezrin / p81

Ezrin / p81

Mouse Monoclonal Antibody [Clone CPTC-Ezrin-1]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Placenta stained with Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1).

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Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1).

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SDS-PAGE Analysis Purified Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1). Confirmation of Purity and Integrity of Antibody

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Western Blot Analysis of SKBr-3, HeLa, HEK293, MCF-7 cell lysates using Ezrin Mouse Monoclonal Antibody (CPTC-Ezrin-1).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using Ezrin / p81 Mouse Monoclonal Antibody (CPTC-Ezrin-1).

Product Details

Synonyms

Villin-2; CVIL; Epididymis secretory protein Li 105; EZR; p81; VIL2; Cytovillin; Cytovillin 2; HEL S 105; DKFZp762H157

Positive Control

SKBr3, HeLa, HEK293, MCF-7, Jurkat, A431, MCF-7. Cerebral cortex and hippocampus.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length Ezrin protein

Cellular Localization

Cell Surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

87kDa

Specificity & Comments

Ezrin, Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70% homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.

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200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Jin, Jingchun, et al. Pathology, BioMed Central, 5 Oct. 2012.

Bioinformatics

  •  Entrez Gene ID: 7430
  •  Gene Symbol: Ezrin
  •  SwissProt: P15311
  •  Chromosome Location: 6q25.3
  •  Unigene: 487027
NBT02238