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Home >> Antibodies >> ENAH / MENA (Actin Regulator)

ENAH / MENA (Actin Regulator)

Mouse Monoclonal Antibody [Clone ENAH/1988]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Western Blot Analysis of human HeLa and MCF-7 cell lysate with ENAH / MENA Mouse Monoclonal Antibody (ENAH/1988).

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SDS-PAGE Analysis Purified ENAH / MENA Mouse Monoclonal Antibody (ENAH/1988). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using ENAH / MENA Mouse Monoclonal Antibody (ENAH/1988)

Product Details

Synonyms

ENA; ENAH; MENA; NDPP1

Positive Control

MCF-7 cells. Uterus.

Known Applications & Suggested Dilutions

ELISA, Western Blot         More Details

ELISA (For coating, order Ab without BSA)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2c, kappa

Mol. Weight of Antigen

80/88/140kDa

Specificity & Comments

The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Stewart, D.M., et al. 1996. J. Clin. Invest. 97: 2627-2634.

Bioinformatics

  •  Entrez Gene ID: 55740
  •  Gene Symbol: ENAH
  •  SwissProt: Q8N8S7
  •  Chromosome Location: Unavailable
  •  Unigene: 497893
NBT01988