2 Union Square, Union City, CA 94587
contact@NeoBiotechnologies.com
510-376-5603

Home >> Antibodies >> Cytokeratin, Multi (Epithelial Marker)

Cytokeratin, Multi (Epithelial Marker)

Recombinant Mouse Monoclonal Antibody [Clone rKRT/457]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Skin stained with Multi-Cytokeratin Mouse Recombinant Monoclonal Antibody (rKRT/457).

img

SDS-PAGE Analysis Purified Multi-Cytokeratin Mouse Recombinant Monoclonal Antibody (rKRT/457).

Product Details

Positive Control

A431 cells, Skin, Colon carcinoma.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Keratin-enriched preparation from cultured human epithelial cells

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Monkey. Cow. Pig. Goat. Rat. Mouse. Guinea Pig. Frog.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

Multiple

Specificity & Comments

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Bartek J et. al. J Pathol, 1991, 164(3):215-24.
  2. Kasper M. Histochemistry, 1991, 95(6):613-20.

Bioinformatics

NBT01876