Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin, HMW Monoclonal Antibody (KRTH/1076).
Formalin-fixed, paraffin-embedded Rat Stomach stained with Cytokeratin, HMW Monoclonal Antibody (KRTH/1076).
Formalin-fixed, paraffin-embedded Rat Oviduct with Cytokeratin, HMW Monoclonal Antibody (KRTH/1076).
SDS-PAGE Analysis Purified Cytokeratin, HMW MAb (KRTH/1076). Confirmation of Purity and Integrity of Antibody.
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
This MAb recognizes basic (Type II or HMW) cytokeratins, which include 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 52kDa (CK8). Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. The acidic keratins have molecular weights (MW) of 56.5, 55, 51, 50, 50', 48, 46, 45, and 40kDa. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.