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Home >> Antibodies >> Cytokeratin 3 (KRT3) (Corneal Epithelial Marker)

Cytokeratin 3 (KRT3) (Corneal Epithelial Marker)

Mouse Monoclonal Antibody [Clone KRT3/2130]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Ovary stained with Cytokeratin 3 Mouse Monoclonal Antibody (KRT3/2130).

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Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin 3 Mouse Monoclonal Antibody (KRT3/2130).

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SDS-PAGE Analysis Purified Cytokeratin 3 Mouse Monoclonal Antibody (KRT3/2130). Confirmation of Purity and Integrity of Antibody.

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Analysis of Protein Array containing more than 19,000 full-length human proteins using Cytokeratin 3 Mouse Monoclonal Antibody (KRT3/2130).

Product Details

Synonyms

65kDa cytokeratin; CK3; Cytokeratin-3; K3; Keratin type II Cytoskeletal-3; Keratin-3; KRT3

Positive Control

A431 cells. Cornea or Skin.

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant full-length human KRT3 protein

Cellular Localization

Cytoplasmic

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

65kDa

Specificity & Comments

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins, which are arranged in pairs of heterotypic keratin chains co-expressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Hanson C., et al. Acta Ophthalmol. 2013 Mar;91(2):127-30.

Bioinformatics

  •  Entrez Gene ID: 38550
  •  Gene Symbol: KRT3
  •  SwissProt: P12035
  •  Chromosome Location: 12q13.13
  •  Unigene: 680652
NBT02130