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Home >> Antibodies >> Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker)

Cytokeratin 19 (KRT19) (Pancreatic Stem Cell Marker)

Recombinant Rabbit Monoclonal Antibody [Clone KRT19/1959R]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
459.00
459.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
459.00
459.00
img

Formalin-fixed, paraffin-embedded human Colon stained with Cytokeratin 19 Rabbit Recombinant Monoclonal Antibody (KRT19/1959R).

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SDS-PAGE Analysis of Purified Cytokeratin 19 Rabbit Recombinant Monoclonal Antibody (KRT19/1959R).

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Western Blot Analysis of Hep-G2 cell lysate using Cytokeratin 19 Rabbit Recombinant Monoclonal Antibody (KRT19/1959R).

Product Details

Synonyms

k19; k1cs; Keratin 19 Keratin Type i 40kD; krt19

Positive Control

Hep-G2; MCF-7, HeLa cells, Breast Cancer.

Known Applications & Suggested Dilutions

Western Blot, IHC-P         More Details

Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant human full-length KRT19 protein

Cellular Localization

Cytoplasmic

Species Reactivity

Human. Mouse.

Host / Ig Isotype

Rabbit / IgG

Mol. Weight of Antigen

40kDa

Specificity & Comments

This Ab reacts with the rod domain of human cytokeratin 19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Nightingale J et. al. J Am SocNephrol 15:21-32 (2004).
  2. Bartek J et. al. Int J Cancer 36:299-306 (1985).
  3. Lewis BC et. al. Genes Dev 17:3127-38 (2003).
  4. Bartek J et. al. J Cell Sci 75:17-33 (1985)

Bioinformatics

  •  Entrez Gene ID: 3880
  •  Gene Symbol: KRT19
  •  SwissProt: P08727
  •  Chromosome Location: 17q21.2
  •  Unigene: 654568
NBT01959