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Home >> Antibodies >> Cystatin A

Cystatin A

Mouse Monoclonal Antibody [Clone CSTA/2882]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Formalin-fixed, paraffin-embedded human Tonsil stained with Cystatin A Mouse Monoclonal Antibody (CSTA/2882).

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Formalin-fixed, paraffin-embedded human Prostate stained with Cystatin A Mouse Monoclonal Antibody (CSTA/2882).

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Analysis of Protein Array containing more than 19,000 full-length human proteins using Cystatin A Mouse Monoclonal Antibody (CSTA/2882).

Product Details

Synonyms

STF1; STFA; AREI; cstA; Stefin A

Positive Control

Human tonsil or prostate tissue (IHC).

Known Applications & Suggested Dilutions

IHC-P         More Details

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Recombinant fragment of human CSTA protein (around aa 1-98) (exact sequence is proprietary)

Cellular Localization

Cell Surface, Cytoplasmic and Nuclear.

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

11kDa

Specificity & Comments

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Takahashi, H., et al. 2001. J. Biol. Chem. 276: 36632-36638.

Bioinformatics

  •  Entrez Gene ID: 1475
  •  Gene Symbol: CSTA
  •  SwissProt: P01040
  •  Chromosome Location: 3Q21.1
  •  Unigene: 518198
NBT02882