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Home >> Antibodies >> CLEC9A

CLEC9A

Rat Monoclonal Antibody [Clone 1F6]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00

Product Details

Synonyms

C type lectin domain family 9, member A; C-type lectin domain family 8 member A; CLEC9A; DNGR1; HEEE9341; PRO34046; UNQ9341; CD370

Positive Control

Mouse spleen.

Known Applications & Suggested Dilutions

Flow Cyt, Western Blot, IF         More Details

Flow Cytometry (1-2ug/million cells)
Western Blot (1-2ug/ml)
Immunofluorescence (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

RBL-2H3 cells expressing Mouse CLEC9A fused to an HA epitope.

Cellular Localization

Membrane

Species Reactivity

Mouse.

Host / Ig Isotype

Rat / IgG1, kappa

Mol. Weight of Antigen

27kDa

Specificity & Comments

This Mab recognizes Mouse DNGR-1, which is also known as CLEC9A, which is a highly specific marker of the CD8a+ and the CD103+ DC subsets, as well as a receptor able to recognize a preformed signal exposed on necrotic cells. In peripheral blood, it is highly restricted on the surface of BDCA31(+) dendritic cells and on a small subset of CD14(+) and CD16(-) monocytes.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Sancho et al. 2008. J Clin Invest 118:2098-110
  2. Sancho et al. 2009. Nature. 458:899-903.

Bioinformatics

  •  Entrez Gene ID: 232414
  •  SwissProt: Q8RU4
  •  Chromosome Location: 6,63.30 (Mouse)
  •  Unigene: 391518
NBT02209