Formalin-fixed, paraffin-embedded normal human spleen tissue stained with CDw75 Mouse Monoclonal Antibody (LN-1).
Surface staining of human lymphocytes with CDw75 Mouse Monoclonal Antibody (LN-1) (red) and isotype control (green). PPI negative population analyzed.
Immunofluorescence Analysis of MeOH-fixed HeLa cells labeled with CDw75 Mouse Monoclonal Antibody (LN-1) followed by goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red).
Known Applications & Suggested Dilutions
Host / Ig Isotype
Mol. Weight of Antigen
Specificity & Comments
Recognizes a neuraminidase-sensitive sialoprotein (CDw75), present on cell membrane and cytoplasm of germinal center B-cells and derived lymphomas. This MAb reacts with RBC precursors of bone marrow, ductal and ciliated epithelial cells of kidney, breast, prostate, pancreas, lung, and with glioblastomas, astrocytomas, and Reed Sternberg cells in lymphocyte predominant Hodgkin s disease. It is shown to be a helpful antibody for ascribing a B-cell phenotype in known lymphoid tissues.