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Home >> Antibodies >> CD79b (B-Cell Marker)

CD79b (B-Cell Marker)

Mouse Monoclonal Antibody [Clone B29/123]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
img

Formalin-fixed, paraffin-embedded human Tonsil stained with CD79b Mouse Monoclonal Antibody (B29/123).

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SDS-PAGE Analysis Purified CD79b Mouse Monoclonal Antibody (B29/123). Confirmation of Purity and Integrity of Antibody.

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Formalin-fixed, paraffin-embedded human Tonsil stained with CD79b Mouse Monoclonal Antibody (B29/123).

Product Details

Synonyms

AGM6; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; Ig-beta; IGB; Immunoglobulin-associated B29 protein

Positive Control

Daudi or Ramos cells. Germinal center B- cells in a lymph node or tonsil.

Known Applications & Suggested Dilutions

IF, Western Blot, IHC-P         More Details

Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)
Optimal dilution for a specific application should be determined.

Immunogen

Synthetic peptide representing the c-terminus from residue 215 of the murine B29 polypeptide.

Cellular Localization

Cell surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG2b, kappa

Mol. Weight of Antigen

39kDa

Specificity & Comments

CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Wood, W.J., Jr., et al. 1993. Genomics 16: 187-192.
  2. Mason, D.Y., et al. 1992. J. Immunol. 22:2753-2756.

Bioinformatics

  •  Entrez Gene ID: 974
  •  Gene Symbol: CD79B
  •  SwissProt: P40259
  •  Chromosome Location: 17q23.3
  •  Unigene: 89575
NBT03107