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Home >> Antibodies >> CD71 / Transferrin Receptor (TFRC)

CD71 / Transferrin Receptor (TFRC)

Mouse Monoclonal Antibody [Clone DF1513]

Catalog #

Size

20 ug
100 ug
100 ug

Price (USD)

199.00
429.00
429.00

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Catalog No

Size

20 ug
100 ug
100 ug

Formulation

Purified Ab with BSA and Azide at 200ug/ml
Purified Ab with BSA and Azide at 200ug/ml
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Price (USD)

199.00
429.00
429.00
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Immunofluorescence Analysis of Human Jurkat cells labeling CD71 with CD71 Mouse Monoclonal antibody (DF1513) followed by Goat anti-Mouse IgG-CF488 (Green). The nuclear counterstain is Reddot (Red)

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Flow Cytometric Analysis of human Jurkat cells using CD71 Mouse Monoclonal antibody (DF1513) followed by Goat anti-Mouse IgG-CF488 (Orange); cells alone (Blue); Isotype Control (Red).

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Western Blot Analysis of Jurkat, Raji, and THP-1 cell lysate using CD71 Mouse Monoclonal antibody (DF1513).

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SDS-PAGE Analysis Purified CD71 Mouse Monoclonal antibody (DF1513). Confirmation of Purity and Integrity of Antibody.

Product Details

Synonyms

Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

Positive Control

CCRF-CEM, Jurkat or K-562. Human placenta or breast carcinoma.

Known Applications & Suggested Dilutions

Flow Cyt, IF, Western Blot         More Details

Flow Cytometry (1-2ug/million cells)
Immunofluorescence (1-2ug/ml)
Western Blot (1-2ug/ml)
Optimal dilution for a specific application should be determined.

Immunogen

KG1 acute myeloid leukemia cell line

Cellular Localization

Cell surface

Species Reactivity

Human.

Host / Ig Isotype

Mouse / IgG1, kappa

Mol. Weight of Antigen

85-95kDa (monomer); 190kDa (dimer)

Specificity & Comments

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa (Workshop IV). This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Related Products



200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Key References

  1. Knapp et al. Leukocyte Typing IV, Oxford Univ Press, Nrs. M15, M15.1, M15.1.1, M15.2, M15.3.1, M15.3.3, M15.4.2, M15.4.3, M15.5.6, M15.5.7, M15.5.9, M16.1, P1.6 and B22.16.

Bioinformatics

  •  Entrez Gene ID: 7037
  •  Gene Symbol: TFRC
  •  SwissProt: P02786
  •  Chromosome Location: 3q29
  •  Unigene: 529618
NBT00188